Profhilo
Remodel. Hydrate. Glow.
A bio‑remodelling treatment that deeply hydrates, firms, and restores natural luminosity.
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What Is This Treatment?
What Is Profhilo?
Profhilo is a bio-remodelling injectable that works at a fundamentally different level from traditional fillers or anti-wrinkle treatments. Rather than adding volume to specific features or relaxing muscles, Profhilo spreads beneath the skin and stimulates your own collagen and elastin production across the entire treated area — delivering comprehensive rejuvenation from within.
The formulation contains one of the highest concentrations of hyaluronic acid available — 64mg per 2ml — using patented NAHYCO® technology that bonds high and low molecular weight HA through heat alone, without chemical cross-linking. This pure, biocompatible product integrates naturally with your tissue, creating a sustained bio-remodelling effect that improves hydration, firmness, elasticity, and overall skin quality.
At Aspire, we administer Profhilo using the distinctive BAP (Bio-Aesthetic Points) technique — just five precise injection points on each side of the face. This minimalist approach delivers maximum results with minimal intervention. Treatment takes 10–15 minutes, requires no numbing cream, and patients return to normal activities immediately. Results are not a “filled” look but genuinely improved skin — more hydrated, firmer, smoother, and visibly more luminous.
“Not filling, not freezing — remodelling your skin at a cellular level for results that are felt as much as seen.”
Ideal Candidates
Is Profhilo Right for You?
Profhilo is suitable for anyone seeking genuine skin quality improvement rather than targeted volume correction. The following indicators suggest you may benefit from a personalised bio-remodelling protocol.
All suitability is confirmed at an initial consultation with our aesthetic practitioner, who will evaluate your skin quality, hydration levels, and treatment objectives.
- Experiencing persistent skin dehydration despite consistent skincare When premium topicals fail to deliver lasting hydration, Profhilo provides deep, sustained moisturisation at a level no cream or serum can replicate.
- Noticing early loss of firmness or mild skin laxity Collagen and elastin stimulation progressively tightens and firms skin across the face, neck, and décolletage — ideal for intervening before laxity becomes more pronounced.
- Wanting whole-face skin improvement rather than isolated correction Unlike fillers that target specific features, Profhilo's spreading bio-remodelling effect upgrades overall skin quality — radiance, texture, elasticity — everywhere it reaches.
- Seeking a natural first step into aesthetic treatments If you are not ready for fillers or surgery, Profhilo offers meaningful, visible improvement with minimal intervention — no frozen look, no volume change, just genuinely better skin.
- Addressing crepey or thinning skin on the neck, chest, or hands These commonly neglected areas age faster than the face. Profhilo restores quality where topical products have reached their limit and fillers are not the appropriate solution.
- Pursuing preventive care in your 30s or restorative care in your 50s and beyond There is no single ideal age. Younger patients preserve skin quality proactively; mature patients reverse established changes. Profhilo benefits skin at every stage.
Your Journey
Your Profhilo Journey
Skin Quality Assessment
We evaluate your skin’s hydration levels, elasticity, firmness, and overall tissue quality. We examine areas of concern — face, neck, décolletage, hands — and discuss your aesthetic goals. We explain how Profhilo’s two-session protocol works, set realistic expectations, and determine whether you are a suitable candidate. Photographs document your starting point for tracking progress.
Protocol Planning
Profhilo requires two treatment sessions spaced four weeks apart. The first primes tissue and initiates collagen and elastin stimulation; the second amplifies and completes the remodelling process. We provide transparent pricing for the complete protocol and discuss whether additional areas — neck, décolletage, hands — would benefit from treatment alongside the face.
First Treatment Session
We cleanse your skin thoroughly — no numbing cream is required, as treatment is minimally uncomfortable. Using ultra-fine needles, we inject small amounts of Profhilo at the five BAP (Bio-Aesthetic Points) on each side of the face. Small bumps appear at each injection site, resembling minor mosquito bites — completely normal and expected. These resolve within 24–48 hours as the product distributes through tissue layers. Most patients describe the sensation as brief pinching lasting seconds per point.
Between-Session Period
Injection-point bumps resolve within 24–48 hours as Profhilo spreads through tissue. Over the following four weeks, you may notice subtle improvements — increased hydration, a slight improvement in firmness, early signs of radiance returning. Avoid aggressive facial treatments during this period, but otherwise resume all normal activities immediately. Optimal results require the second session.
Second Treatment Session
Identical to the first treatment — same BAP injection points, same quick procedure. This second session amplifies the bio-remodelling effect initiated by the first. The combined impact of both sessions creates the comprehensive skin quality transformation that defines Profhilo’s results.
Results Development
Progressive improvement occurs over the weeks following your second treatment as collagen and elastin production reaches its peak. Skin becomes visibly more hydrated, firmer, smoother, and more radiant. Fine lines soften, texture improves, and overall appearance is refreshed. Peak results typically appear 8–12 weeks after the second session.
Maintenance
Results typically last 6–9 months. We recommend a maintenance protocol — two sessions again, four weeks apart — every 6–12 months to sustain and build upon improvements. With consistent maintenance, skin quality continues to improve cumulatively over time.
2 sessions, 4 weeks apart
Protocol
10–15 minutes
Treatment Time
8–12 weeks
Peak Results
6–9 months
Duration
Body Areas
Where Can Profhilo Be Used?
Face
Comprehensive facial rejuvenation
The most common treatment area. Profhilo’s BAP technique ensures even distribution across the entire face — cheeks, temples, around the eyes, forehead, and jawline — for whole-face skin quality improvement rather than isolated correction. Ideal if: Your skin has lost its radiance, feels dehydrated despite good skincare, or you want genuine skin quality improvement without the “filled” look of traditional injectables.
Neck
Crepey skin, horizontal lines, laxity
Ageing neck skin responds exceptionally well to Profhilo’s bio-remodelling effect. Improves crepiness, horizontal necklace lines, and mild laxity. Often treated alongside the face for a seamless result. Requires a different injection-point pattern than the face. Ideal if: Your neck is ageing faster than your face and you want to close the gap without invasive intervention.
Décolletage
Chest crepiness, sun damage, texture
Sun-damaged, crepey chest skin sees significant improvement in smoothness, hydration, and firmness. Restores quality to this often-neglected but highly visible area. Ideal if: You avoid open necklines because of chest crepiness or sun damage, and topical treatments have not delivered meaningful results.
Hands
Volume loss, visible tendons, crepiness
Improves crepey texture on the backs of the hands and reduces the visibility of veins and tendons. Creates more youthful, fuller-looking hands with improved hydration and skin quality. Ideal if: Your hands reveal your age more than your face does, and you want a non-surgical approach to hand rejuvenation.
Inner Arms
Upper arm crepiness, mild sagging
Addresses crepey, thinning skin on the inner upper arms. Improves texture and mild laxity in this area that is resistant to exercise and topical treatments alone. Ideal if: Skin laxity on your upper arms affects your confidence in sleeveless clothing, and you prefer a non-invasive approach.
Above Knees
Knee crepiness, skin sagging
Crepey, sagging skin above the knees responds to Profhilo treatment, improving texture and mild laxity. Results vary and may require additional sessions for this area. Ideal if: Knee-area crepiness is a concern and you are looking for a treatment option where surgery is not appropriate or desired.
Clinical Excellence
The Science Behind Profhilo
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NAHYCO® Technology
Unlike traditional HA fillers that use chemical cross-linking agents (BDDE), Profhilo uses patented thermal bonding to hybridise high and low molecular weight hyaluronic acid through heat alone. The result is a pure, biocompatible product — 64mg of HA per 2ml, one of the highest concentrations available — that integrates naturally with tissue and provides sustained bio-remodelling rather than quick absorption.
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BAP Injection Technique
The Bio-Aesthetic Points technique uses just five precise injection points on each side of the face, positioned where skin naturally drapes and moves. These points align with fascial planes, allowing optimal product spread with minimal injection trauma. The minimalist approach — ten points total — delivers maximum coverage while keeping treatment quick and comfortable.
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Four-Type Collagen and Elastin Stimulation
Clinical studies demonstrate that Profhilo stimulates production of Collagen Types I, III, and IV alongside elastin — the key structural proteins that diminish with ageing. This multi-type stimulation creates genuine tissue remodelling rather than temporary volumising, with measurable improvements in firmness, elasticity, and hydration.
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Spreading and Integration
After injection, Profhilo’s low viscosity allows it to spread beneath the skin, distributing evenly across the treatment area rather than remaining in an injection pocket. This creates a diffuse, natural effect — whole-area skin quality improvement rather than localised correction. The product attracts and retains moisture deep within tissue, providing hydration beyond what any topical product can achieve.
Radiant Skin Transformation
“My neck and décolletage were becoming crepey and aged-looking. After completing the Profhilo protocol on my face, neck, and chest, my skin looks years younger. It is smooth, firm, and hydrated. I feel confident wearing anything now.”
Radiant Skin Transformation
“I was not ready for fillers, but my skin looked tired and dull despite investing in good skincare. Profhilo was the perfect first step — my skin is now plump, glowing, and radiant. People constantly ask what I have changed. The improvement is subtle but unmistakable.”
Radiant Skin Transformation
“As a man, I wanted improvement without looking treated. Profhilo was ideal — my skin looks healthier and more vital, but completely natural. The treatment was quick and nearly painless. Colleagues say I look more rested and energetic.”
Radiant Skin Transformation
“At my age, I did not think much could be done without surgery. Profhilo proved me wrong. My skin is visibly firmer, smoother, and more hydrated. The crepiness around my eyes and mouth has reduced dramatically. It has given me confidence I thought I had lost.”
Common Questions
Profhilo Questions
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What is the difference between Profhilo and dermal fillers?
They work in fundamentally different ways. Dermal fillers add volume to specific features — lips, cheeks, jawline — and stay where they are injected. Profhilo spreads beneath the skin and remodels tissue quality across the entire treatment area. It does not add volume to individual features; it improves hydration, firmness, elasticity, and radiance everywhere. Think of fillers as sculpting individual features and Profhilo as upgrading your skin’s overall quality.
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Does Profhilo hurt?
Most patients rate discomfort at 2–3 out of 10 — a brief pinching sensation lasting seconds per injection point. No numbing cream is needed, and it is actually not recommended as it can interfere with product distribution. Profhilo is one of the most comfortable injectable treatments available. The small bumps left at injection points are not painful, just temporarily noticeable.
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Why do I need two sessions?
The two-session protocol is how Profhilo works optimally — this is clinical design, not upselling. The first session primes your tissue and initiates the bio-remodelling process. The second, four weeks later, amplifies and completes the collagen and elastin stimulation. Clinical studies demonstrate significantly better results with two treatments versus one. A single session does provide some benefit, but the two-session protocol is the established standard for optimal outcomes.
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When will I see results?
Subtle improvement appears 2–4 weeks after the first session — increased hydration and early radiance. Visible results develop 4–8 weeks after the second session as collagen and elastin production builds. Peak results typically occur at 8–12 weeks after the second treatment. The transformation is progressive and natural — you will not have a dramatic overnight change, but gradual, genuine improvement.
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How long do results last?
Typically 6–9 months, with some patients enjoying results for up to 12 months. Longevity depends on age, skin condition, lifestyle, and individual metabolism. We recommend a maintenance protocol — two sessions again — every 6–12 months to sustain and build upon improvements. With regular maintenance, results become cumulative.
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Will the bumps be obvious after treatment?
The injection-point bumps are visible and slightly raised immediately after treatment, resembling small mosquito bites. Most patients find them significantly reduced within 24 hours and completely resolved by 48 hours. If you have an important event, schedule treatment at least 2–3 days in advance. The bumps are not painful and do not interfere with normal activities.
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Can I combine Profhilo with other treatments?
Yes — Profhilo combines exceptionally well with other aesthetics treatments. Anti-wrinkle injections can be performed on the same day or spaced apart. Dermal fillers are usually spaced two weeks from Profhilo, with Profhilo often administered first to improve the skin “canvas” before targeted filler placement. Micro-needling and chemical peels should be spaced 2–4 weeks apart. Profhilo frequently serves as a foundation treatment in comprehensive rejuvenation programmes.
Begin Your Journey
Discover Bio-Remodelled Skin
Experience the transformative power of Profhilo — genuine skin quality improvement from within, in two simple sessions.
Complementary Treatments
Explore Our Aesthetic Range
Smoothing · Anti-Wrinkle Injections
Address dynamic wrinkles while Profhilo improves overall skin quality. A powerful combination for comprehensive facial rejuvenation.
Volume · Dermal Fillers
Profhilo improves the canvas; fillers sculpt specific features. Often used together for complete rejuvenation — Profhilo first, then targeted filler placement.
Regeneration · Polynucleotides
Both are regenerative treatments. Polynucleotides complement Profhilo’s bio-remodelling with enhanced cellular repair and tissue quality improvement.